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Conolidine’s analgesic consequences stem from its conversation with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors in the central anxious method, conolidine modulates alternate molecular targets. A Science Developments study found that conolidine interacts Along with the atypical chemokine receptor ACKR3/CXCR7,

" Thus far, the compound has revealed remarkably several, if any, Unwanted effects, but that is one thing of a double-edged sword. "The lack of Unwanted effects makes it a very good applicant for advancement," Bohn mentioned. "Alternatively, if there have been Negative effects, they may supply further clues as to how the compound operates within th

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